Ziana gel is a combination of clindamycin 1% and tretinoin 0.025%. Clindamycin is an antibiotic and fights bacteria in the body. Tretinoin is a form of vitamin A and it reduces the amount of oil released by oil glands in your skin, it also helps your skin to renew itself more quickly. Ziana gel is used to treat severe nodular acne in adults and children who are at least 12 years old.
Wash your hands before applying this medication. Gently clean the affected skin with a mild/soapless cleanser and pat dry. Use your fingertips to apply a small amount of medication (about the size of a pea) in a thin layer over the face, usually once daily at bedtime or as directed by your doctor. Be careful to avoid the eyes and lip area. Use this medication on the skin only. Wash your hands after using the medication to avoid accidentally getting it in your eyes. During the first few weeks of using this product, your acne might appear worse because the medication is working on pimples forming inside the skin. It may take several weeks to notice results from this medication. Use it regularly on a daily basis. Do not use a larger amount or use it more frequently than recommended as your skin will not improve any faster but your risk of redness, peeling and pain will increase.
Do not apply to the inner lip area or inside the nose/mouth. Do not apply to cut, scraped, sunburned, or eczema-affected skin. Avoid getting this medication in your eyes. If this occurs, flush with large amounts of water. Call your doctor if eye irritation develops. Women who are pregnant or who may become pregnant should not use Ziana since this medication is absorbed through the skin and may harm an unborn baby. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Ziana can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun. Your skin may be more sensitive to weather extremes such as cold and wind. Protect your skin with clothing and use a moisturizing cream or lotion as needed.
To make sure Ziana is safe for you tell your doctor if you have any allergies and a history of stomach or intestinal disorders. You should not use this medication if you have Crohn's disease, inflammation of your intestines (also called enteritis), ulcerative colitis or if you have ever had severe diarrhea caused by antibiotic medicine.
Possible side effect
Get emergency medical help if you have any of these signs of an hives, difficult breathing, swelling of your face, lips, tongue or throat, severe redness, burning, stinging or scaling of treated skin areas, diarrhea that is watery or bloody.
You should not use Ziana if you are also taking another antibiotic called erythromycin or using other skin medications that contain erythromycin.
Take the missed dose as soon as possible. Skip the missed dose if it is time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention if you think you have used too much of this medicine.
Store your medicines at room temperature between 59-77 degrees F (15-25 degrees C). Do not freeze. Store away from moisture and light. Keep it out of the reach of children and away from pets.
The information presented at the site has a general character. Note please this information cannot be used for self-treatment and self diagnosis. You should consult with your doctor or health care adviser regarding any specific instructions of your condition. The information is reliable, but we concede it could contain mistakes. We are not responsible for any direct, indirect, special or other damage caused by use of this information on the site and also for consequences of self-treatment.